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Validating a spatio-temporal model of observed neighborhood physical disorder

https://doi.org/10.1016/j.sste.2022.100506

Plascak, Jesse J. ; Mooney, Stephen J. ; Schootman, Mario ; Rundle, Andrew G. ; Llanos, Adana A.M. ; Qin, Bo ; Hong, Chi-Chen ; Demissie, Kitaw ; Bandera, Elisa V ; Xu, Xinyi ( June 2022 , Spatial and Spatio-temporal Epidemiology)

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Associations between neighborhood disinvestment and breast cancer outcomes within a populous state registry

https://doi.org/10.1002/cncr.33900

Plascak, Jesse J. ; Rundle, Andrew G. ; Xu, Xinyi ; Mooney, Stephen J. ; Schootman, Mario ; Lu, Bo ; Roy, Jason ; Stroup, Antoinette M. ; Llanos, Adana A. ( January 2022 , Cancer)

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Gestational weight change and childhood body composition trajectories from pregnancy to early adolescence

https://doi.org/10.1002/oby.23367

Widen, Elizabeth M. ; Burns, Natalie ; Daniels, Michael ; Backlund, Grant ; Rickman, Rachel ; Foster, Saralyn ; Nichols, Amy R. ; Hoepner, Lori A. ; Kinsey, Eliza W. ; Ramirez‐Carvey, Judyth ; et al ( March 2022 , Obesity)

Abstract Objective
A mother–child dyad trajectory model of weight and body composition spanning from conception to adolescence was developed to understand how early life exposures shape childhood body composition.
Methods
African American (49.3%) and Dominican (50.7%) pregnant mothers (n= 337) were enrolled during pregnancy, and their children (47.5% female) were followed from ages 5 to 14. Gestational weight gain (GWG) was abstracted from medical records. Child weight, height, percentage body fat, and waist circumference were measured. GWG and child body composition trajectories were jointly modeled with a flexible latent class model with a class membership component that included prepregnancy BMI.
Results
Four prenatal and child body composition trajectory patterns were identified, and sex‐specific patterns were observed for the joint GWG–postnatal body composition trajectories with more distinct patterns among girls but not boys. Girls of mothers with high GWG across gestation had the highest BMIzscore, waist circumference, and percentage body fat trajectories from ages 5 to 14; however, boys in this high GWG group did not show similar growth patterns.
Conclusions
Jointly modeled prenatal weight and child body composition trajectories showed sex‐specific patterns. Growth patterns from childhood though early adolescence appeared to be more profoundly affected by higher GWG patterns in females, suggesting sex differences in developmental programming.

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